Herod the Great
Herod murdered two of his brothers-in-law, Mariamne (his second wife), his mother-in-law, and three of his sons (Alexander and Aristobulus from Mariamne; Antipater from his first wife, Doris). The Emperor, Caesar Augustus, is said to have said, "It is better to be Herod's pig than his son." He had ten wives in all. Cf: "Herod the Great."